Palabras clave
Biotechnology
Enzyme Stability Biocatálisis
Biotecnología
Inmovilización enzimática
Cómo citar
Resumen
La biocatálisis es el uso de enzimas para acelerar las reacciones químicas y posee innegables ventajas sobre la catálisis convencional, ya que disminuye sensiblemente el uso de compuestos tóxicos y disolventes, genera menos residuos peligrosos, y permite trabajar en condiciones menos agresivas de temperatura y pH, a pesar de estas bondades, las enzimas, por su naturaleza proteica, pueden ser fácilmente desnaturalizadas y al ser solubles, no son recuperables del medio de reacción, por ello, la inmovilización enzimática es una especialidad de la biocatálisis en constante desarrollo y crecimiento ya que permite una mayor estabilidad, reuso y fácil recuperación del medio, su aplicación es ya generalizada y va en aumento en industrias tales como la farmacéutica, la de los biocombustibles, la alimentaria y de producción de sabores, fragancias y cosméticos. Las diferentes estrategias para obtener derivados inmovilizados se abordan en el presente documento.
Enzyme immobilization strategies
Abstract: Biocatalysis is the use of enzymes to accelerate chemical reactions and has undeniable advantages over conventional catalysis, since it significantly reduces the use of toxic compounds and solvents, generates less hazardous waste, and allows working in less aggressive conditions of temperature and pH, Despite these benefits, enzymes due to their protein nature can be easily denatured and being soluble, they are not recoverable from the reaction medium, therefore, enzymatic immobilization in a specialty of biocatalysis in constant development and growth since it allows a greater stability, reuse and easy recovery of the medium, its use is already widespread and is increasing in industries such as pharmaceuticals, biofuels, the food industry and the production of flavors, fragrances and cosmetics. The different strategies to obtain immobilized derivatives are addressed in this document.
Citas
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Derechos de autor 2023 Ghian Emir Sosa Parra, Rodolfo Quintana-Castro, Rosa María Oliart-Ros, Alfonso Alexander-Aguilera, MARÍA-GUADALUPE SÁNCHEZ-OTERO